Docosanol (Abreva) is another treatment option. It’s an over-the-counter cream that can shorten an outbreak by anywhere from a few hours to a day. The cream must be applied several times per day. Medications Cold sores can also be treated with oral antiviral medications, such as acyclovir (Zovirax), valacyclovir (Valtrex), and famciclovir (Famvir). These drugs are available by prescription only. Your doctor may instruct you to take antiviral medications regularly if you’re experiencing complications with cold sores or if your outbreaks are frequent. Home remedies Symptoms may be eased by applying ice or washcloths soaked in cold water over the sores. Alternative treatments for cold sores include using lip balm containing lemon extract. Taking lysine supplements on a regular basis is associated with less frequent outbreaks for some people. Aloe vera, the cooling gel found inside the leaves of the aloe plant, may bring cold sore relief. Apply aloe vera gel or aloe vera lip balm to a cold sore three times a day. A petroleum jelly such as Vaseline won’t necessarily heal a cold sore, but it may ease discomfort. The jelly helps prevent cracking. It also serves as a protective barrier against outside irritants. Witch hazel is a natural astringent that may help dry out and heal cold sores, but it can sting with application. Scientists in one studyTrusted Source demonstrated that witch hazel has antiviral properties that may inhibit the spread of cold sores. Even so, the verdict is still out on whether cold sores heal faster if they’re kept moist or dry. Always apply home remedies, creams, gels, or ointments to cold sores using a clean cotton swab or cotton ball.

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